财政补贴是否使癌症基因测试在社会经济群体中的普及程度相等? 在新加坡进行了一项回顾性观察性研究
Akshar Saxena1, Renne Phay2, Jianbang Chiang2,3
1Division of Economics, Nanyang Technological University, Singapore.
BMJ open
|December 8, 2025
概括
财政补贴显著增加了癌症遗传测试的普及率,特别是在较低社会经济地位 (SES) 的人群中. 年龄和癌症阶段等意识因素也会影响检测率,改善平等的获取.
科学领域:
- 遗传学 遗传学 是一个
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
背景情况:
- 社会经济地位 (SES) 和财政补贴可能会影响获得癌症遗传检测的机会.
- 了解影响测试普及的因素对于公平的医疗保健服务至关重要.
研究的目的:
- 调查SES,财政补贴和认识因素 (年龄,癌症阶段,家族病史) 与癌症遗传检测的吸收之间的联系.
- 评估这些因素在确保公平获得遗传检测服务方面的作用.
主要方法:
- 在新加坡 (2014-2020年) 对2687名接受遗传性癌症综合征预测咨询的人进行了回顾性队列研究.
- 主要结果:基因检测的普及. 解释变量:SES (住房指数),补贴状况,年龄,癌症阶段,家庭病史.
- 分析检查了跨SES和年龄的子组变化.
主要成果:
- 财政补贴与更高的基因测试使用率有很强的相关性 (aOR 9.15).
- 受补贴的个体的吸收率>90%,而非受补贴的个体的吸收率为56-68%,在最低的SES群体中获得的收益最大.
- 年龄较小,癌症晚期,以及家族病史 (尤其是患有癌症的孩子) 与吸收增加有关.
结论:
- 财政补贴是癌症基因测试普及的关键驱动力.
- 补贴似乎减轻了差异,在较低的SES和老年人群中显示出更大的影响.
- 解决金融障碍对于公平获得基因测试至关重要.
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