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Updated: Jan 9, 2026

Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase G6PI-Induced RA Mice
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微生物三甲基胺抑制IRAK4会抑制代谢炎症,并改善血糖控制

Julien Chilloux1, Francois Brial2, Amandine Everard3,4

  • 1Section of Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

Nature metabolism
|December 8, 2025
PubMed
概括

肠道微生物代谢物三甲基胺 (TMA) 通过抑制IRAK4.4将炎症和胰岛素抵抗与肥胖脱. 这一发现为影响2型糖尿病代谢和免疫健康的微生物化合物提供了新的见解.

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