韩国的一只斑点海 (Phoca largha) 中的Pseudolactococcus raffinolactis菌株GCULR的完整基因组序列
Tae Seon Cha1, Soojin Lim2, Keeman Lee1
1Department of Food Science and Biotechnology, College of Bionano Technology, Gachon University, Seongnam, 13120, Republic of Korea.
BMC genomic data
|December 9, 2025
概括
来自韩国斑点海的Pseudolactococcus raffinolactis菌株GCULR的基因组测序揭示了其作为益生菌的潜力. 这项研究增强了对海洋哺乳动物有益细菌的理解.
科学领域:
- 微生物学 微生物学
- 基因组学就是基因组学.
- 海洋哺乳动物健康
背景情况:
- 牛奶酸细菌Pseudolactococcus raffinolactis对益生菌和食品应用非常有希望.
- 海洋哺乳动物拥有独特的微生物群落,这些微生物群落可能具有有益的特性.
研究的目的:
- 为了执行从一条状斑点海中分离的P. raffinolactis菌株GCULR的全基因组测序.
- 为了解海洋哺乳动物中的有益细菌及其生态作用提供基因组数据.
主要方法:
- 使用PacBio和Illumina X-10平台对P. raffinolactis菌株GCULR的隔离和全基因组测序.
- 生物信息分析包括基因注释,比较基因组学和功能集群的识别 (例如,细菌素).
主要成果:
- 拉菲诺拉克蒂斯 (P. raffinolactis) 的完整基因组是单个圆形染色体 (2.270.555 bp),具有2.260个注释基因.
- 对比分析证实与食品衍生的分离物具有很高的相似性,而基因组查发现了潜在的毒性和抗菌素耐药性基因,以及一种细菌素集群.
- 基因组包含两个完整的prophage区域,有助于理解它的遗传构成.
结论:
- P. raffinolactis GCULR的基因组序列为从海洋哺乳动物宿主中获得的这种细菌的遗传构成提供了宝贵的见解.
- 这些发现突出了来自海洋环境的P. raffinolactis对于益生菌应用的潜力,并扩大了对该物种多样性的知识.
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