在老年人中,sarcopenic肥胖症和6年以上认知表现和微妙认知障碍的纵向轨迹
Héctor Vázquez-Lorente1,2,3, Indira Paz-Graniel1,2,3, Hernando J Margara-Escudero1,2,3
1Universitat Rovira i Virgili. Departament de Bioquímica i Biotecnologia, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Reus, Spain.
Journal of cachexia, sarcopenia and muscle
|December 9, 2025
概括
肥胖症与老年人的长期认知能力下降有关. 这种情况可能是随着时间的推移导致认知功能下降的独立风险因素.
科学领域:
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
- 代谢健康 代谢健康
背景情况:
- 在老年人群中,sarcopenic肥胖症是越来越令人担忧的.
- 它作为认知衰退的危险因素的作用需要进一步的前性调查.
研究的目的:
- 为了研究基线形肥胖症和6年认知轨迹之间的关联.
- 为了评估老年人与sarcopenic肥胖症微妙的认知障碍的风险.
主要方法:
- 对1097名55-75岁的超重/肥胖和代谢综合征的成年人进行了长度研究.
- 根据欧洲共识标准定义的sarcopenic肥胖症;在6年内评估认知功能.
- 统计模型分析了认知表现和微妙认知障碍的风险.
主要成果:
- 在6年内,sarcopenic肥胖与全球和一般认知功能的较大下降有关.
- 患有sarcopenic肥胖症的个体患有微妙的全球认知障碍的风险更高.
- 单独的萨尔科佩尼亚或肥胖症并没有与认知能力下降有显著的关系.
结论:
- 肥胖症可能是认知能力下降的独立的长期风险因素.
- 需要进一步临床评估萨科佩尼性肥胖对认知的影响.
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