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在阿尔茨海默氏症进展过程中,USP10在tau病理和神经元命运中的双重调控作用

Masahiko Takahashi1, Hiroki Kitaura2,3, Asa Nakahara2

  • 1Division of Virology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Molecular and cellular biology
|December 9, 2025
PubMed
概括

乌比基特异性蛋白酶10 (USP10) 对于阿尔茨海默病 (AD) 中的神经元存活至关重要. 降低USP10会在晚期AD中恶化Tau病理和神经元损失.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.塔乌·塔乌 (Tau Tau) 是一个神经元细胞死亡 神经元细胞死亡泛基素特异性蛋白酶10 (USP10) 的使用

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