膀高度宽度比作为预测未来的神经性膀功能障碍在患有直肠形的患者
Shinsuke Yoshizawa1, Kensuke Ohashi1, Tetsuya Ishimaru2
1Department of Pediatric Urology, Saitama Children's Medical Center, Saitama, JPN.
Cureus
|December 9, 2025
概括
膀高度宽度比 (HWR) 可以预测神经性膀功能障碍 (NBD) 的新生儿与直肠形 (ARMs). 一个HWR截止值为1.842显示了这些患者早期风险分层的希望.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 新生儿手术 新生儿手术
- 医疗成像医学成像
背景情况:
- 阳道形 (ARMs) 是一种先天性疾病,可能导致神经性膀功能障碍 (NBD).
- 早期识别新生儿患有ARM的NBD风险对于及时干预和管理至关重要.
- 膀高度宽度比 (HWR) 是一种超声波测量,可能表明膀异常.
研究的目的:
- 评估膀高度宽度比 (HWR) 作为神经性膀功能障碍 (NBD) 的潜在预测因子,在新生儿中具有高和中等直肠形 (ARMs).
- 确定特定的HWR值,以识别 NBD 风险较高的新生儿.
主要方法:
- 对48名患有高或中等ARM的新生儿进行回顾性审查,这些新生儿接受了腹腔镜辅助直肠整形手术.
- 测量最大膀高度宽度比 (HWR) 从产后不久进行的囊囊造影.
- 将患者分为NBD (需要干净间歇性导管 - CIC) 和非NBD组.
主要成果:
- 与非NBD组 (n=40,中位数HWR1.432;p=0.000029) 相比,NBD组 (n=8) 的中位数HWR (1.942) 显著更高.
- HWR切线值为1.842,显示了高灵敏度 (92.5%) 和特异性 (75%) 预测需要CIC (AUC=0.888).
- 圣器形与NBD显著相关 (OR 10.76,p=0.0006),而脊柱异常和遗传异常则没有.
结论:
- 在出生后不久,新生儿患有高和中等ARM的高HWR可能作为预测NBD的早期查工具.
- 建议HWR值为1.842,作为该人群风险分层的潜在切线.
- 在ARM患者中,圣器形与NBD有很强的关联,这凸显了全面评估的重要性.
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