心理健康状况和心血管状况在"生活必需品"八大类别中的结果
1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, No. 2, Anzhen Road, Chao Yang District, Beijing, 100029, China.
概括
焦虑和抑郁等心理健康状况显著增加心血管疾病的风险,特别是与较低的心血管健康 (CVH) 评分相结合时. 这种风险甚至存在于中等至最佳CVH的个体中.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 焦虑和抑郁是已知的心血管疾病 (CVD) 的风险因素.
- 心理健康对心血管健康 (CVH) 不同水平的心血管健康 (CVH) 结果的影响尚未得到充分理解.
- 心血管健康是使用生命必需8 (LE8) 评分来衡量的.
研究的目的:
- 调查心理健康状况与心血管结果之间的关联.
- 检查心血管健康水平如何改变这种关联.
主要方法:
- 对290,778名没有先前心血管疾病的英国生物库参与者的分析.
- 使用LE8得分对CVH进行评估.
- 通过问卷和ICD-10代码确定心理健康状况 (健康,仅焦虑,仅抑郁,并发性焦虑和抑郁).
- 考克斯的比例危险模型经过对混因素进行调整,并根据LE8分数进行分层 (<50 [不良CVH]与≥50 [中等最佳CVH]).
主要成果:
- 伴随性焦虑和抑郁症显示了最高的整体心血管风险 (调整HR为1.85).
- 在CVH差 (LE8 <50) 个体中,焦虑,抑郁和并发症都增加了心血管风险 (调整后HRs为1.23-1.46).
- 在中等最佳CVH (LE8 ≥50) 个体中,焦虑,抑郁和并发症也增加了心血管风险 (调整后HRs为1.39-1.78).
结论:
- 心理健康状况独立地影响心血管风险.
- 心理健康对心血管风险的影响是由基线心血管健康改变的.
- 心理健康是心血管风险的重要预测因素,即使在良好的CVH患者中也是如此.
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