在多发性骨髓瘤中散布的肺部参与:CT上罕见的外骨髓性表现
Akshay Kumar1, Gaurav Raj1, Kaustubh Gupta1
1Department of Radiodiagnosis, Dr Rmlims, sc rai hostel rmlims , 226010, Lucknow, Uttar Pradesh, India.
Radiology case reports
|December 9, 2025
概括
多发性骨髓瘤 (MM) 的肺部参与是罕见的,具有诊断挑战. 这一案例凸显了基因病理学的必要性,以确认肺部的外骨髓瘤,即使使用暗示性成像.
科学领域:
- 血液学 血液学 血液学
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
背景情况:
- 多发性骨髓瘤 (MM) 很少影响肺部,经常模仿其他肺部疾病.
- 在MM患者中,外脊髓性疾病存在诊断困难,因为症状与感染和其他癌症重叠.
研究的目的:
- 在多发性骨髓瘤中报告肺部参与的病例.
- 强调诊断方面的挑战和组织病理学确认的重要性.
主要方法:
- 一个61岁的男性患有已知的MM和呼吸道症状的病例介绍.
- 高分辨率计算机断层扫描 (HRCT) 用于肺部成像.
- 用CT指导的活检进行基因病理学分析,包括CD138和kappa轻链限制染色.
主要成果:
- 人体肺复原试验显示了随机分布的肺结节和间歇性加厚.
- 组织病理学证实了单克隆血细胞透,与外骨髓性肺髓瘤一致.
- 通过将成像与活检结果的相关性来确立诊断.
结论:
- 肺部参与MM是一种罕见但显著的表现.
- 准确的诊断需要将HRCT发现与组织病理学结合起来.
- 早期诊断外骨髓性肺髓瘤对于患者管理至关重要.
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