复发性复发性多发性硬化症中的语义网络表现出效率,相互连接性和灵活性降低
Sophia Lall, Jennifer Pardo, Joshua Sandry1
1Department of Psychology, Montclair State University, Montclair, NJ, USA.
概括
患有复发性复发性多发性硬化症 (pwRRMS) 的人遇到难以寻找单词的困难. 语义网络分析揭示了 pwRRMS 中的语义检索是无组织的,与标准流利性测试不同.
科学领域:
- 神经学 神经学
- 认知科学 认知科学
- 语言学的语言学.
背景情况:
- 在患有复发性缓解性多发性硬化症 (pwRRMS) 的人群中,词汇寻找缺陷很普遍.
- 这些缺陷可能源于无效的语义信息组织.
- 了解这些认知挑战对于管理这种疾病至关重要.
研究的目的:
- 在 pwRRMS.中调查语义组织和检索.
- 为了比较pwRRMS和健康对照之间的语义网络拓.
- 评估主观的词搜索问题与客观措施之间的关系.
主要方法:
- 利用了来自64个 pwRRMS和73个对照组的语义流性数据.
- 使用语义网络和流利实用程序R套件推导出标准的口语流利度.
- 在SemNet R包中使用基于关联的网络方法构建语义网络.
主要成果:
- PwRRMS报告了比控制更频繁的词查找问题.
- 在标准的语义流度测量中没有发现显著差异.
- PwRRMS显示了变化的语义网络拓,包括效率降低,互连性和灵活性.
结论:
- 难以找到单词是很常见的,应该在 pwRRMS 中进行选.
- 语义网络分析比标准指标更敏感,用于检测 pwRRMS 中的语义检索缺陷.
- 语义网络的混乱可能是词查找问题的基础;针对网络结构的干预措施可能是有益的.
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