[阻塞性睡眠呼吸暂停作为血管性认知障碍中认知障碍的加重因素]
1Smolensk State Medical University, Smolensk, Russia.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|December 9, 2025
概括
严重阻塞性睡眠呼吸暂停综合征 (OSAS) 在患有血管性认知障碍 (VCD) 的患者中显著恶化认知功能并增加抑郁症状. 这项研究强调了对执行职能和处理速度的影响.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 血管认知障碍 (VCD) 是认知衰退的重要原因之一.
- 阻塞性睡眠呼吸暂停综合征 (OSAS) 是一种常见的并发症,可能会加剧VCD.
- 严重的OSAS对VCD患者认知功能和心理健康的影响需要进一步阐明.
研究的目的:
- 评估严重OSAS对中度VCD患者认知功能的影响.
- 为了评估VCD患者的焦虑抑郁症状的严重程度,有或没有严重的OSAS.
- 在这个人群中,确定受严重OSAS影响最严重的特定认知领域.
主要方法:
- 51名中度VCD患者被分为具有 (n=26) 和没有 (n=25) 严重OSAS的组.
- 通过心肺呼吸监测 (严重OSAS的AHI≥30) 确认了OSAS的诊断.
- 认知功能和心理症状使用MoCA,BDI,STAI,FAB,FCSRT-IR和SDMT进行了评估.
主要成果:
- 患有严重OSAS的患者在FAB,SDMT,FCSRT-IR和MoCA上得分明显较低,这表明认知障碍更大.
- 严重的OSAS组表现出更高的抑郁症状率 (BDI总和体质-情感分级).
- 在严重的OSAS组中,观察到低水平的状态焦虑 (STAI-S).
结论:
- 严重的OSAS加剧了中度VCD患者的认知缺陷,特别是影响执行功能,处理速度和精神运动反应.
- 严重的OSAS存在与抑郁症状的增加有关,而状态焦虑水平仍然很低.
- 这些发现强调了在VCD患者中查和管理OSAS的重要性,以减轻认知和心理衰退.
更多相关视频
04:53Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
1.3K
06:23A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
Published on: September 22, 2020
6.0K
相关概念视频
Sleep Apnea
452
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
452
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
517
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
517
Substance Use Disorders Affecting Sleep
369
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
369
Insufficient Sleep and Sleep Deprivation
807
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
807
Alzheimer's Disease: Overview
1.6K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.6K
Dementia
487
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
487
