相关实验视频
Updated: Jan 7, 2026
08:50
Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
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[免疫疗法开始后的伪进展]
Michael Winkelmann1,2,3, Matthias Kassube1, Philipp Linden1
1Klinik und Poliklinik für Radiologie, LMU Klinikum, München, Marchioninistr. 15, 81377, München, Deutschland.
Radiologie (Heidelberg, Germany)
|December 9, 2025
概括
区分伪进步和真正的进步是很有挑战性的. 建议在怀疑伪进展的稳定患者中继续早期免疫治疗并进行成像随访.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 核医学就是核医学.
背景情况:
- 从真正的瘤进展区分伪进展是一个重要的临床和放射学挑战.
- 像CT,MRI和FDG-PET/CT这样的既定方法在确定诊断方面存在局限性.
研究的目的:
- 审查当前和新兴的方法,以区分伪进展与癌症治疗患者的真正进展.
- 突出新方法的潜力,并提供临床建议.
主要方法:
- 审查已建立的放射性成像技术,包括计算机断层扫描 (CT),磁共振成像 (MRI) 和氧糖-正子辐射断层扫描/计算机断层扫描 (FDG-PET/CT).
- 探索创新方法,如新的PET/CT标记剂,液体活检和放射学.
- 对这些技术的性能进行临床研究数据的分析.
主要成果:
- 标准的成像方法 (CT,MRI,PET/CT) 提供线索,但往往没有确定性.
- 实验室标记和放射学等新的方法显示出希望,但需要进一步的临床验证和采用.
- 目前正在进行的临床研究正在研究新的成像技术.
结论:
- 在临床稳定的患者中,在开始免疫疗法后怀疑伪进展,需要继续治疗.
- 密切的成像随访 (例如,在4-8周) 对于监测疑似伪进展的患者至关重要.
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