聚乙烯终止时间:一个新的切除成功的实时预测器
Keijiro Nakamura1,2, Naohiko Sahara3, Jumpei Yamamoto3
1Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, 2-22-36 Ohashi, Meguro-ku, Tokyo, 153-8515, Japan. nakamura1-04@live.jp.
概括
聚乙烯终止时间 (PTT) 比局部激活时间 (LAT) 更好地预测成功的聚乙烯切除. 25秒的PTT截止时间提供了指导,但解剖学变异需要考虑.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 在过早心室收缩 (PVC) 切除中优化结果需要实时操作员反.
- 假设PVC终止时间 (PTT),即从射频发射到PVC消失的间隔,可以比局部激活时间 (LAT) 更好地预测急性成功.
研究的目的:
- 为了评估PTT与LAT在PVC废除程序中的预测值.
- 确定PTT是否是一种优越的实时指标,用于评估PVC切除的急性成功.
主要方法:
- 分析了54名患者的310次废除应用,测量了PTT和LAT.
- 为了评估预测准确性,进行了接收器操作特征 (ROC) 和后勤回归分析.
- 进行了特定位置的分析和长期随访,以评估复发率.
主要成果:
- 在92.6%的患者中,急性除成功.
- 较短的PTT (中位数为12s vs. 62s) 和较早的LAT (-36ms vs. -26.5ms) 与成功的切除相关.
- 与LAT (AUC=0.72) 相比,PTT显示出更高的预测准确性 (AUC=0.93),25秒的截止值显示88%的灵敏度和83%的特异性.
结论:
- PTT 作为急性 PVC 切除成功的实用,实时预测器,性能优于 LAT.
- 25秒的PTT切线为程序成功提供了客观指导,同时考虑了解剖学变异.
- 长期随访证实了PTT在预测没有复发的有效性.
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