了解癌症和多病症患者不坚持慢性药物的原因:一种定性研究
Deborah R Kaye1,2,3,4,5, Roshni Varma6, Sophia Roud7
1Department of Urology, Duke University School of Medicine, Durham, NC, USA.
Journal of general internal medicine
|December 9, 2025
概括
患有癌症和多种慢性疾病的患者由于竞争的优先事项和相互矛盾的医疗建议,难以遵守药物治疗. 需要进行干预措施,以支持这些患者管理复杂的治疗方案.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 药理学 药理学是指药理学的学科.
背景情况:
- 患有多种疾病 (≥2种慢性疾病) 的患者在癌症诊断后,往往会经历非癌症药物的坚持下降.
- 这种不遵守会增加疾病进展,住院和死亡的风险.
- 了解降低坚持的原因对于有效的患者管理至关重要.
研究的目的:
- 在多病症和活跃癌症患者中对影响慢性药物坚持的障碍和促进者的定性探索.
主要方法:
- 半结构面试对20名成年患者 (≥50岁) 进行了采访,这些患者在过去一年内被诊断出患有癌症,并管理了≥2种慢性疾病.
- 参与者接受了积极的癌症治疗,并从学术卫生系统中招募.
- 应用主题分析被用来分析采访成绩单.
主要成果:
- 1) 癌症,慢性病和预约之间的优先级冲突,往往导致忽视慢性病管理.
- 2) 对医疗保健提供者的信任和自信显著影响了执业动机.
- 3) 物流方面的挑战,包括副作用,药物相互作用和不同护理团队的相互矛盾的建议,阻碍了遵守.
结论:
- 患有癌症和多病症的患者在同时管理多种治疗和医疗保健提供者方面面临重大挑战.
- 相互矛盾的建议和后勤困难造成了实质性的药物遵守障碍.
- 有针对性的干预措施是必要的,以改善这种脆弱患者群体的药物坚持和结果.
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