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Updated: Jan 7, 2026

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针对患者相关的结构:审查体温生物大分子及其配体,用于制药应用

Alice Brink1, John R Helliwell2, Francois J F Jacobs1

  • 1Chemistry Department, University of the Free State, Nelson Mandela Drive, Bloemfontein, South Africa.

Acta crystallographica. Section D, Structural biology
|December 9, 2025
PubMed
概括

在37°C确定宏分子结构为药物开发提供了与患者相关的见解. 虽然具有挑战性,但适应37°C和更高温度的结晶学方法对了解蛋白质功能和药物结合变异有希望.

关键词:
37°C的温度可以.在PDBCSD调查中,身体的温度 身体的温度衍射结构生物学结构生物学这些人是超热友好型的.生理条件生理条件的生理条件.热爱的人是热爱的人.

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