两个无关病毒的异步病毒传播确定了菜大静脉疾病 症状发展
Willem E W Schravesande1,2, Peter M de Heer3, Maurice Heilijgers4
1University of Amsterdam Faculty of Science, Molecular Plant Pathology, Amsterdam, Netherlands.
Phytopathology
|December 9, 2025
概括
大静脉疾病是由两个病毒引起的,即大静脉相关病毒 (LBVaV) 和米拉菲奥里大静脉病毒 (MiLBVV). LBVaV的传播先于MiLBVV,保留的RNA丰度表明了调节作用和独立的进化.
科学领域:
- 植物病毒学 植物病毒学
- 农业科学 农业科学
- 菌类学 菌类学是指菌类学.
背景情况:
- 大静脉病 (LBVD) 严重影响全球生产.
- LBVD与两个不同的病毒有关:米拉菲奥里大静脉病毒 (MiLBVV) 和大静脉相关病毒 (LBVaV).
- 这两种病毒都是由土壤传播的真菌Olpidium virulentus*传播的,但它们的个别作用和相互作用仍然不清楚.
研究的目的:
- 为了调查 MiLBVV 和 LBVaV 在生病的生菜中的流行率和相互作用.
- 了解每个病毒在受感染植物中的系统传播动态.
- 分析两种病毒的基因组特征和进化模式.
主要方法:
- 使用来自LBVD感染地区的含有*O. virulentus*子的土壤样本进行感染测定.
- 在菜根和芽中检测和定量MiLBVV和LBVaV.
- 全基因组分析以研究病毒段重组和进化速率.
主要成果:
- 在患病的生菜中始终检测到LBVaV,而MiLBVV的患病率较低,但与严重症状相关.
- 从根到芽的LBVaV系统传播始终在MiLBVV传播之前,并且高度同步.
- 全基因组分析表明独立的细分重组和保存的RNA细分丰度,表明调节作用.
- 病毒ORF的不同进化速率表明病毒适应性的潜在漏洞.
结论:
- LBVaV在LBVD中扮演着一致的角色,其传播时间早于MiLBVV.
- RNA 分段的丰富性似乎是每个病毒独立的保存调节因素.
- 病毒基因组分析揭示了通过利用不同的进化速率来管理LBVD的潜在目标.
更多相关视频
11:12Protocols for Investigating the Host-tissue Distribution, Transmission-mode, and Effect on the Host Fitness of a Densovirus in the Cotton Bollworm
Published on: April 12, 2017
8.9K
06:01Testing the Physiological Barriers to Viral Transmission in Aphids Using Microinjection
Published on: May 14, 2008
12.4K
相关概念视频
00:57Viral Recombination
24.9K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
24.9K
01:29Subviral Agents
475
Subviral agents are infectious entities that resemble viruses but lack one or more viral components, such as a capsid or essential replication machinery. These agents include viroids, prions, and satellites, each possessing distinct structural and functional characteristics that influence their mode of infection and replication.Viroids are the simplest subviral agents, consisting of circular, single-stranded RNA molecules without a protein coat. They exclusively infect plants, relying entirely...
475
01:51Mechanisms of Retrovirus-induced Cancers
6.8K
Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
6.8K
01:30Venous Thrombosis I: Introduction
310
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
310
01:20Infection
11.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
11.6K
01:03Rous Sarcoma Virus (RSV) and Cancer
6.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
6.1K