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IL-27促进CD122的Treg细胞表达和在恒常状态中的适应性

Zachary R Lanzar1, Daniel L Aldridge1, Elisa Cruz-Morales1

  • 1Department of Pathobiology, University of Pennsylvania, Philadelphia, PA 19104.

Proceedings of the National Academy of Sciences of the United States of America
|December 9, 2025
PubMed
概括

干白素-27 (IL-27) 信号增强调节性T (Treg) 细胞的竞争力和生存,通过促进CD122的表达,这对免疫平衡至关重要. 这种细胞因子通过提高对生长因子的反应能力来塑造Treg细胞池的组成.

关键词:
在IL-27和IL-27之间.这就是Treg Treg.竞争 竞争 竞争 竞争 竞争 竞争细胞因子细胞因子恒常状态 (homeostasis) 是一种平衡状态.

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