微生物饮食相互作用和个性化营养
Magdalena Kujawska1,2,3, Lindsay J Hall2,3,4,5
11ZIEL - Institute for Food & Health, Technical University of Munich, Freising, Germany;
Annual review of food science and technology
|December 9, 2025
概括
精准营养,考虑个体肠道微生物群的个人资料,为代谢健康提供量身定制的饮食建议. 技术的进步正在改善个性化的饮食预测,但研究标准化和多样化的队列对其成功至关重要.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 代谢健康 代谢健康
背景情况:
- 营养对宿主生理学和肠道微生物群组成有深远的影响.
- 肠道微生物群与饮食的相互作用影响代谢健康.
- 对于肥胖和2型糖尿病等疾病,饮食反应的个体间变化是显著的.
研究的目的:
- 探索精密营养的潜力,包括个体微生物组的个人资料.
- 突出先进技术在个性化营养中的作用.
- 识别微生物组信息营养中的障碍和挑战.
主要方法:
- 高通量测序用于微生物组分析.
- 用于生物化学分析的代谢学.
- 机器学习用于饮食结果的预测建模.
主要成果:
- 越来越多的证据支持精准营养,以提供量身定制的饮食建议.
- 技术进步正在使个性化的饮食结果预测成为可能.
- 方法的异质性和有限的人口多样性是已知的障碍.
结论:
- 精准营养,由微生物组提供信息,对代谢健康有希望.
- 研究方法的标准化和在不同的队列中验证是必不可少的.
- 解决数据隐私等伦理问题对于公平获得个性化营养工具至关重要.
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