冠状动脉计算机断层扫描血管学在心房患者的协议和性能:系统性审查和元分析
X-Z Yang1, S Hachaichi2, J Endrikat3
1Bayer China, Medical Department. Chaoyang District 100020 Beijing, China.
Clinical radiology
|December 9, 2025
概括
使用iopromide对比剂的冠状动脉计算机断层扫描血管学 (CCTA) 在心房动 (AF) 患者中有效诊断冠状动脉疾病 (CAD). 优化的协议和扫描仪提高图像质量,同时减少辐射暴露.
科学领域:
- 心血管成像 - 心血管成像
- 放射学 放射学是指放射学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 心房动 (AF) 对于使用计算机断层扫描血管学 (CCTA) 诊断冠状动脉疾病 (CAD) 提出了挑战.
- 对于AF患者的CCTA中IOPROMIDE对比剂的性能需要进行系统的评估.
研究的目的:
- 系统地调查IAF患者的IOPROMIDE对比度增强CCTA用于CAD的协议和诊断性能.
- 评估图像质量,辐射剂量和诊断准确度指标.
主要方法:
- 在PubMed,Embase,Web of Science和Cochrane图书馆的系统文献搜索,截至2025年2月.
- 对14项研究 (601名患者) 的元分析,使用iopromide 370 mgI/ml CCTA.
- 对诊断部分,有效辐射剂量,灵敏度,特异性和ROC曲线的聚合分析.
主要成果:
- 98%的细分被诊断为患有AF的患者 (95% CI:0.96-0.99).
- 每个患者的ROC为0.97 (95%CI:0.95-0.98);每个细分的ROC为0.99 (95%CI:0.98-0.99).
- 个性化协议和高性能扫描仪改善了图像质量;前性协议减少了约50%的辐射剂量.
结论:
- 伊奥普罗米德370 mgI/mlCCTA在AF患者中提供一致的图像质量和准确的CAD诊断.
- 高性能扫描仪,个性化的协议和潜在的采集可以提高图像质量并减少辐射暴露.
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