机器学习确定创伤经历与非临床人口和被诊断患有精神病的个体的听觉语言幻觉有关
Dijana Ostojic1, Fergus Quilligan2, Dara M Cannon2
1Centre for Neuroimaging, Cognition and Genomics (NICOG), University of Galway, Ireland; School of Biological and Chemical Sciences, University of Galway, Ireland.
Psychiatry research
|December 9, 2025
概括
创伤经历,痛苦和焦虑是听觉语言幻觉 (AVHs) 的关键预测因素. 机器学习分析表明,这些因素可能会先于AVH,为精神病提供潜在的时间洞察力.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
背景情况:
- 听觉语言幻觉 (AVH) 是精神病的一个核心症状.
- 在一般人群中,AVH影响5-28%的人.
研究的目的:
- 在临床和非临床人群中确定AVH的强有力的预测因素.
- 利用机器学习来分析各种预测变量.
主要方法:
- 在英国生物库数据上使用XGBoost分类算法.
- 分析了临床 (n=938) 和非临床 (n=132,236) 样本.
- 包括社会人口统计,环境,生物,心理和健康措施.
主要成果:
- 样本中一致的预测因素:被动自杀念头,痛苦,创伤,焦虑,教育程度.
- 非临床样本:童年创伤,抑郁,大麻吸烟.
- 临床样本:自我伤害,睡眠剥夺,双相情感障碍多原风险评分 (PRS).
- 只有AVH样本的精神病预测因素:精神困扰,寻求专业帮助,自我伤害,精神分裂症PRS,就业状况.
结论:
- 机器学习确定了AVHs的显著预测因素.
- 创伤经历显示出潜在的时间预测器的AVHs.
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