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慢性呼吸道疾病中咳评估 (COASESS):从一个前性的多中心横截面研究的结果

Tai Joon An¹, Hyeon-Kyoung Koo², Chin Kook Rhee³

¹Division of Pulmonary and Critical Care Medicine, Department of Internal medicine, Yeouido St. Mary`s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Tuberculosis and respiratory diseases

|December 9, 2025

概括

慢性咳 (CC) 的特征在喘和异常性肺纤维化 (IPF) 等呼吸道疾病中显著不同,影响生活质量. 针对疾病的具体评估对于有效管理持续性咳至关重要.

科学领域:

呼吸系统医学呼吸系统医学
临床的表型化临床的表型化
症状负担评估症状负担评估

背景情况:

慢性咳 (CC) 是慢性呼吸系统疾病的普遍症状,包括喘,异常性肺纤维化 (IPF),慢性阻塞性肺病 (COPD) 和支气管切除 (BE).
在这些不同的疾病中,CC的特定特征和对患者生活质量的影响仍然不完全理解.
了解这些差异对于开发有针对性的诊断和治疗策略至关重要.

研究的目的:

在患有各种慢性呼吸道疾病的患者中全面描述慢性咳 (CC).
评估咳强度,频率,生活质量和过敏度在喘,IPF,COPD和BE之间的差异.
识别咳表现和触发器中的潜在疾病特异性模式.

主要方法:

一项多中心,前性,横截面研究 (COASESS) 涉及266名患有慢性呼吸道疾病的患者.
使用经过验证的工具来评估咳强度 (NRS),频率 (CSS),生活质量 (COAT,LCQ) 和咳过敏度 (CHQ).
人口统计数据包括年龄,性别和吸烟情况也被收集和分析.

主要成果:

人口特征的显著差异被观察到:喘患者年轻,女性更多,非吸烟者,而COPD和IPF患者年长,男性,一直吸烟者.
与COPD和BE患者相比,喘和IPF患者报告的症状负担更大,生活质量更差,这是COAT,LCQ,NRS和CSS得分所表明的.
虽然整体咳过敏度得分 (CHQ) 相似,但喘患者报告说,更频繁的触发因素,如说话和鼻后滴水.

结论:

在不同的慢性呼吸道疾病中存在慢性咳的不同表型特征.
喘和IPF与更高的症状负担和对生活质量的更大影响有关.
咳过敏和触发因素可能因潜在的呼吸系统疾病而异,这强调了需要特定疾病的治疗方法.

关键词:

喘喘是一种支气管切除症是一种支气管切除症.慢性阻塞性肺病慢性阻塞性肺病慢性咳一种慢性咳.咳过敏症咳过敏症异形性肺纤维化症异形性肺纤维化症结构性肺部疾病结构性肺部疾病

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