在患有和没有青光眼的患者中评估干眼调查问卷
Giulia Coco1, Giulia Piccotti2, Leopoldo Rossi2
1Ophthalmology Unit, Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy giulia.coco@uniroma2.it.
The British journal of ophthalmology
|December 9, 2025
概括
眼皮表面疾病指数 (OSDI) 和其他干眼疾病 (DED) 调查问卷在青光眼患者中表现不同. 与DEQ-5和SANDE不同的是,OSDI相关性在晚期玻璃眼中减弱,这表明问卷选择影响了DED症状评估.
科学领域:
- 眼科医生 眼科 眼科
- 干眼疾病研究 干眼疾病研究
- 玻璃眼研究研究研究
背景情况:
- 干眼病 (DED) 显著影响患者,问卷对症状评估至关重要.
- 一种渐进的视神经病变 - - 玻璃眼 - - 可能与DED同时存在或被DED加剧.
- 标准化的DED问卷包括眼睛表面疾病指数 (OSDI),DEQ-5和SANDE.
研究的目的:
- 为了比较OSDI,DEQ-5和SANDE在患有和没有青光眼的患者中的性能.
- 为了评估青光眼的严重程度如何影响DED问卷结果.
- 为了确定问卷的选择是否会影响DED患者的DED症状检测.
主要方法:
- 一项涉及147名患者的横截面研究,这些患者接受了视野 (VF) 测试并填写了DED问卷.
- 根据平均偏差 (MD) 值,格劳科马的严重程度被分为轻度,中度或高级.
- 分析包括问卷和线性回归之间的对对相关性,用于预测因素.
主要成果:
- 在非青光眼和轻度至中度青光眼组中,OSDI与DEQ-5和SANDE显示了中度至高的相关性.
- 在晚期青光眼中,OSDI,DEQ-5和SANDE之间的相关性变得较低且无意义.
- DEQ-5和SANDE在所有青光瘤阶段 (r≥0.66;p<0.01) 始终保持显著的相关性.
- OSDI是唯一一个受平均MD (p=0.002) 显著影响的问卷.
- 与DEQ-5相比,使用OSDI的眼患者更频繁地被确定为DED的症状 (65.4%与51.9%相比;p=0.0082).
结论:
- DED问卷显示了绿眼病患者的多样性行为.
- OSDI与其他DED问卷的相关性在晚期玻璃眼症下降.
- 选择问卷对于准确捕捉绿眼的DED症状至关重要,特别是在晚期.
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