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Updated: Jan 9, 2026

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功能性基因组学用于改进收养T细胞移植疗法.

Joseph G Skeate1,2,3, Chang-Jung Lee3,4, Carli Stewart5,6,7

  • 1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.

Journal for immunotherapy of cancer
|December 9, 2025
PubMed
概括

使用CRISPR和睡眠美女转体子突变发生的前向遗传选识别了新的遗传标,以提高固体瘤中采用细胞治疗 (ACT) 的有效性. 这些工具克服了瘤微环境和T细胞枯竭等挑战,改善了ACT的耐用性.

关键词:
收养细胞疗法 - ACT基因组 基因组 基因组 基因组 基因组下一代测序 - - 国家基因系统 (NGS)瘤微环境 - - 瘤微环境

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