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Updated: Jan 9, 2026

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作为对RBM39降解剂的反应,神经母细胞瘤状态的转录和表观遗传分析

Hongjian Jin1, Jie Fang2, Jason Myers3

  • 1Center for Applied Bioinformatics, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee, 38105, USA. Hongjian.Jin@stjude.org.

Scientific data
|December 9, 2025
PubMed
概括

神经母细胞瘤复发是由治疗耐药的细胞驱动的,这些细胞在上腺素 (ADRN) 和介质细胞 (MES) 状态之间切换. 印苏拉姆治疗揭示了神经母细胞瘤中这种血统可塑性和耐药性的机制.

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Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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