相关实验视频

Updated: Jan 9, 2026

Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Manner
09:02

Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Manner

Published on: December 10, 2015

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通过FAM222蛋白质的结构建模进行进化分析,揭示了脊椎动物的一种新型无序保存域,该域与NLK相互作用

Eduardo Calvario1, Lorenzo Segovia2, Mario Zurita3

  • 1Departamento de Genética del Desarrollo y Fisiología Molecular 1, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av Universidad 2001, Col. Chamilpa, Mexico City, 62250, Mexico.

Scientific reports
|December 9, 2025
PubMed
概括

内在无序区域 (IDR) 对于细胞信号传递至关重要. 这项研究显示,DCD222,FAM222蛋白中保存的IDR,结合Nemo-like kinase (NLK),调节其活性而不阻断催化.

关键词:
阿尔法Fold3是什么意思本质上是无序的区域.在MAPK信号传输中.尼莫类激酶. 尼莫类激酶.蛋白质的进化是如何发生的

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In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay08:56

In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay

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