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Updated: Jul 4, 2026

Operant Procedures for Assessing Behavioral Flexibility in Rats
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皮质激素通过背上条纹体的可塑性相关基因表达加速行为不灵活性

Michael D Murphy1, Keegan S Krick1, Shuo Zhang2

  • 1Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
|December 9, 2025
PubMed
概括

慢性压力激素皮质 (CORT) 通过改变大脑中的基因表达来损害行为灵活性. 这项研究揭示了CORT诱导的纹状体表观遗传变化,影响突触可塑性并导致不灵活的行为.

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