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Updated: Jan 9, 2026

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通过LINE1调节元件,通过组织基因甲基转移酶EHMT2对与全能相关的基因位点进行协调抑制

Kaushiki Chatterjee1, Christopher Mitsuo Uyehara1, Kritika Kasliwal1

  • 1Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10065, USA.

EMBO reports
|December 9, 2025
PubMed
概括

染色体抑制剂EHMT2通过抑制关键发育基因,防止小鼠胚胎干细胞 (mESCs) 成为两细胞类细胞 (2CLCs). 它的耗尽促进了过渡,揭示了多能性的机制.

关键词:
在EHMT2中使用.H3K9 甲基化 甲基化线路-1 线路-1 在线多能性是一种多能性.在Totipotency中使用.

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