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一种简单的基于碳的电化学/光电化学双模式吸食传感器,用于检测亚毒素B1

Yijun Tan¹, Dan Meng², Fang Li³

¹Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin, 300134, China.

Analytical and bioanalytical chemistry

|December 9, 2025

概括

这项研究介绍了一种用于检测亚毒素B1 (AFB1) 的新型双模式传感器. 电化学/光电化学 (EC/PEC) 传感器提供了一种具有高灵敏度的自验证机制,用于AFB1检测.

科学领域:

纳米复合材料是一种材料.
生物感知技术的技术
分析化学是一种分析化学.

背景情况:

开发敏感和选择性的方法来检测菌毒素,如亚毒素B1 (AFB1) 对于食品安全至关重要.
现有的检测方法往往缺乏自我验证或需要复杂的程序.

研究的目的:

为AFB1检测开发一种双模式电化学/光电化学 (EC/PEC) 传感平台.
创建一个自我验证的传感机制,以提高可靠性.

主要方法:

碳点/液体剥皮石墨烯 (CDs/LEG) 纳米复合材料平台的制造.
使用双信号探针:用铁标记的阿普坦 (Fc-Apt) 和用甲蓝标记的补充DNA (MB-cDNA).
利用AFB1结合的竞争性位移和形状变化来调节EC和PEC信号.

主要成果:

双模式传感器显示出协同反应,在EC模式下增强信号比率 (I_Fc/I_MB),在PEC模式下减少信号.
在广泛的AFB1度范围内 (0.01-100 ng/mL) 实现了优异的线性.
获得的低检测极限为1.356 pg/mL (EC模式) 和0.087 pg/mL (PEC模式).

结论:

开发的基于CD/LEG的双模式传感器为AFB1检测提供了一个独特的自我验证机制.
该平台具有高灵敏度和可靠性,适用于食品安全监测的实际应用.

关键词:

AFB1 是一个空军基地.碳点是一些碳点.双模式的口味传感器液体脱皮石墨烯是一种液体脱皮石墨烯.

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