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Updated: Jan 9, 2026

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里卢盐酸盐中的三态化:选,晶体结构和溶液热力学

Alexander P Voronin1, Anna G Ramazanova1, Anna V Vologzhanina2

  • 1G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, 1 Akademicheskaya St., 153045, Ivanovo, Russia.

Pharmaceutical research
|December 9, 2025
PubMed
概括

研究了riluzole盐酸盐中的多态性,以改善药物特性. 发现了两种新形式,其中形式3提供可调节的溶解度和溶解,以优化药物输送.

关键词:
结晶/盐的形成.溶解溶解是一种解体.制药盐 制药盐是一种药用盐.阶段过渡 阶段过渡多形态主义的多态主义.溶解度 溶解度 溶解度 溶解度

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Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
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