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急性复杂分泌体炎保守治疗失败的预测因素:单中心回顾性分析
Cataldo De Palma1, Simone Giudici2,3, Paolo Enrico Meneghesso2
1Digestive and General Surgery Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089, Rozzano, Milan, Italy. cataldo.depalma@st.hunimed.eu.
Updates in surgery
|December 9, 2025
概括
对急性复杂分泌体炎 (ACD) 的保守治疗在20.5%的病例中失败. 肥胖和大腹腹是ACD患者治疗失败的关键预测因素.
科学领域:
- 胃肠病学 胃肠病学
- 外科胃肠道外科手术
- 腹部外科手术 腹部外科手术
背景情况:
- 根据WSES指南,保守/非手术治疗是急性复杂分泌体炎 (ACD) 的首要方法.
- 治疗失败可能导致住院,成本,发病率和死亡率增加.
研究的目的:
- 为了确定ACD中非操作性管理的失败率.
- 为了确定非手术治疗失败的潜在预测因素在ACD患者.
主要方法:
- 在2017年1月至2021年12月期间入院的164名白炎患者的回顾性分析.
- 评估患者的人口统计,炎症标志物,放射学发现,管理和结果.
- 统计分析包括单变量和多变量评估,以确定故障预测因素.
主要成果:
- 在130名ACD患者中,112人接受了非手术治疗;23人 (20.5%) 失败.
- 单变分析表明男性性别,肥胖 (BMI>30),ASA>2,瘤>4厘米与失败有关.
- 多变量分析确定肥胖 (OR 2.92) 和腹腔内> 4厘米 (OR 3.66) 是失败的显著预测因素.
结论:
- 对ACD的非操作性管理具有显著的失败率.
- 肥胖和大腹部是非手术治疗失败的重要预测因素.
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