Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

12.1K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
12.1K
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

14.7K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
14.7K
Cryo-electron Microscopy01:28

Cryo-electron Microscopy

4.1K
Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
4.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Long-lived multilevel coherences and spin-1 dynamics encoded in the rotational states of ultracold molecules.

Nature communications·2025
Same author

Long-lived entanglement of molecules in magic-wavelength optical tweezers.

Nature·2025
Same author

A motorized rotation mount for the switching of an optical beam path in under 20 ms using polarization control.

The Review of scientific instruments·2023
Same author

Sticky collisions of ultracold RbCs molecules.

Nature communications·2019

相关实验视频

Updated: Jan 9, 2026

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
10:20

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

Published on: September 5, 2019

8.7K

显微镜中的多态检测和空间定位用于超冷分子.

Jonathan M Mortlock1, Adarsh P Raghuram2, Benjamin P Maddox2

  • 1Department of Physics, Durham University, South Road, Durham, DH1 3LE, United Kingdom. jonathan.m.mortlock@durham.ac.uk.

Nature communications
|December 9, 2025
PubMed
概括

我们开发了一种新方法,可以实时检测单个超冷分子及其状态. 这种技术允许精确测量分子性质,这对于量子气体显微镜和先进的分子物理实验至关重要.

更多相关视频

Picometer-Precision Atomic Position Tracking through Electron Microscopy
15:04

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

8.2K
Conducting Multiple Imaging Modes with One Fluorescence Microscope
08:32

Conducting Multiple Imaging Modes with One Fluorescence Microscope

Published on: October 28, 2018

10.2K

相关实验视频

Last Updated: Jan 9, 2026

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
10:20

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

Published on: September 5, 2019

8.7K
Picometer-Precision Atomic Position Tracking through Electron Microscopy
15:04

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

8.2K
Conducting Multiple Imaging Modes with One Fluorescence Microscope
08:32

Conducting Multiple Imaging Modes with One Fluorescence Microscope

Published on: October 28, 2018

10.2K

科学领域:

  • 量子物理学的量子物理学
  • 超冷的原子和分子.
  • 量子气体显微镜的使用方法

背景情况:

  • 精确测量超冷分子对于量子气体实验至关重要.
  • 目前的方法缺乏在批量样本中检测单个分子的分辨率.

研究的目的:

  • 为了证明在现场检测单个超冷分子.
  • 为了能够精确地测量分子特性,如密度和内部状态.

主要方法:

  • 使用来自原子量子气体显微镜的技术.
  • 将分子固定在一个二维光学格子中并将它们分离.
  • 从构成原子中采集光,以高NA的目标.

主要成果:

  • 实现了单分子检测分辨率,直到亚微米格子间距.
  • 能够精确测量密度依赖的碰撞损失.
  • 证明了分子位置和旋转状态的同时检测.

结论:

  • 开发的方法提供了前所未有的访问单个超冷分子的属性.
  • 这种技术对于推进超冷分子气体和量子模拟研究至关重要.