关于老年人类骨遗骸的DNA研究的全球趋势:一个图书识别分析 (1989-2024年)
Jiao Luo1, Zhiqi Hua1, Ji Chen1
1Institute of Forensic Science, Fudan University, No. 131 Dongan Road, Xuhui District, Shanghai, 200032, PR China.
International journal of legal medicine
|December 9, 2025
概括
对古代人类骨遗骸的DNA分析对法医科学和人类学至关重要. 研究表明,古代DNA (aDNA) 越来越多地被整合到法医工作流程中,特别是使用线粒体DNA (mtDNA) 和SNP分析.
科学领域:
- 法医遗传学 法医遗传学
- 法医人类学 法医人类学
- 考古学的考古学
- 生物信息学是一种生物信息学.
背景情况:
- 对老年人类骨遗骸的DNA分析对多个科学学科至关重要.
- 了解这个研究领域的演变和趋势对于未来的进展至关重要.
研究的目的:
- 分析出版趋势,主要贡献者,有影响力的期刊和老年人类骨遗骸DNA分析领域的主题演变.
- 确定主导主题和最近的技术进步.
- 突出国际合作的影响.
主要方法:
- 从科学网络核心收藏中对982篇出版物的图书法分析.
- 使用VOSviewer和Biblioshiny进行网络分析和可视化.
- 采用了共同作者网络,关键字共同出现和时间叠加映射.
主要成果:
- 该领域的出版物始于1989年,在2021年达到峰值,共有72篇文章.
- 美国,德国,英国,意大利和西班牙是最多产的国家.
- 关键主题包括古代DNA (aDNA),人类骨遗骸,线粒体DNA (mtDNA),法医科学和人类识别.
- 最近的趋势显示,aDNA在法医,mtDNA和SNP分析以及对退化的DNA进行大规模并行测序 (MPS) 的使用增加.
结论:
- 技术创新和国际合作已经大大改变了这个领域.
- 持续的全球合作对于推进法医遗传学研究至关重要.
- 集成先进的DNA分析技术对于法医应用至关重要.
相关概念视频
Next-generation Sequencing
97.6K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
97.6K
Sanger Sequencing
772.8K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
772.8K
Maxam-Gilbert Sequencing
12.5K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
Challenges of the Maxam-Gilbert Method
The...
12.5K
Bone Disorders
5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
Evolutionary Relationships through Genome Comparisons
6.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.8K
The Fossil Record
27.0K
The fossil record documents only a small fraction of all organisms that have ever inhabited Earth. Fossilization is a rare process, and most organisms never become fossils. Moreover, the fossil record only exhibits fossils that have been discovered. Nevertheless, sedimentary rock fossils of long-lived, abundant, hard-bodied organisms dominate the fossil record. These fossils offer valuable information, such as an organism's physical form, behavior, and age. Studying the fossil record helps...
27.0K


