在埃塞俄比亚选定的医院住院的PLHIV患者中,死亡率和相关因素:一项横截面研究
Abeje Kebede1, Derbachew Asfaw Teni2, Wegene Tamene2
1Ethiopian Public Health Institute, Addis Ababa, Ethiopia. abeje_k@yahoo.com.
BMC infectious diseases
|December 9, 2025
概括
埃塞俄比亚艾滋病毒感染者 (PLHIV) 住院患者的死亡率为13.2%,男性,老年人和患有机会性感染或不活跃ART的人面临更高的风险. 干预措施应解决这些因素,以改善患者的治疗结果.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 人类免疫缺陷病毒 (HIV) 仍然是一个重要的全球卫生问题,特别是在资源有限的环境中.
- 艾滋病毒感染者 (PLHIV) 仍然存在高死亡率.
- 关于埃塞俄比亚艾滋病毒死亡率的数据有限,需要进一步调查.
研究的目的:
- 为了确定在埃塞俄比亚医院住院的PLHIV患者的死亡率.
- 为了确定与这种患者群体的死亡率相关的因素.
主要方法:
- 进行了基于设施的回顾性横截面研究.
- 分析了来自埃塞俄比亚37家医院的10,077名PLHIV的数据 (2016年1月至2023年12月).
- 统计分析包括描述性,双变量和多变量后勤回归.
主要成果:
- 住院PLHIV患者的整体死亡率为13.2%.
- 死亡率的预测因素包括男性性别,年龄较大 (45-54岁和≥55岁),入院时的机会性感染 (OI),非传染性疾病 (NCD) 和并发症,以及不活跃的抗逆转录病毒治疗 (ART) 状态.
- 具体来说,入院时的OIs显著增加了死亡风险 (AOR=2.25).
结论:
- 在埃塞俄比亚,大约八分之一的入院PLHIV患者在住院期间死亡.
- 死亡率与男性性别,晚年,OI,非传染性疾病,并发症和不活跃的ART状态显著相关.
- 加强医疗保健系统以性别特定的干预措施和对OI和并发性疾病的常规查至关重要.
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