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Updated: Aug 3, 2026

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调查PTPN11基因在乳头甲状腺癌的预后潜力:大量和单细胞转录组的综合研究

Huiling Wang1,2, Mian Lv1,2, Yonghong Huang1,2

  • 1Department of Breast and Thyroid Surgery, The Second Nanning People's Hospital, Nanning, Guangxi, PR China.

Medicine
|December 10, 2025
PubMed
概括

蛋白氨酸酸酶非受体类型11 (PTPN11) 显示在乳头甲状腺癌 (PTC) 的预后价值. 这项研究确定了与PTPN11相关的基因和关键细胞,为PTC治疗策略提供了新的见解.

关键词:
胰腺癌是一种癌症.皮囊甲状腺癌 皮囊甲状腺癌预测风险模型的预测风险模型.一个单细胞转录组的转录组.

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Tumor Progression02:07

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...