哈蒙尼跨导管肺门外压缩:实验室测试和案例报告
Mary Breige O'Donnell-Smith1, Daniel S Levi2,3, Gentian Lluri3
1Division of Pediatric Cardiology, University of Washington School of Medicine, Seattle Children's Hospital, Seattle, Washington, USA.
概括
本案例研究表明,Harmony门在一个手术生物假体和冠状动脉压缩失败的患者中成功使用. 门 门是一个门.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 生物医学工程 生物医学工程
背景情况:
- 一名45岁的男性患有先天性肺狭窄症,在手术生物假体安置后发生肺吐.
- 冠状动脉压缩 (左前下降) 发生在气球造术期间,排除气球可扩展植入.
研究的目的:
- 评估Harmony门在非合规着陆区的可行性和性能,并有可能对冠状动脉进行压缩.
- 在各种压缩场景下评估门体压缩和水力动力性能.
主要方法:
- 在循环和圆压缩下对Harmony门 (TPV22和TPV25) 进行ex vivo水力动力测试.
- 用定制固定装置尺寸对患者进行特定的测试,以模拟不同的压缩水平.
- 在实验室评估后,在患者体内植入Harmony TPV25门.
主要成果:
- 基板测试证明了在模拟压缩下门的性能.
- 哈蒙尼TPV25门已成功地植入患者体内.
- 植入后观察到优异的即时和中期结果.
结论:
- 对于那些在具有挑战性的解剖部位上失败的手术生物假体患者来说,Harmony门是一个可行的选择,即使有冠状动脉压缩的风险.
- 这一案例凸显了Harmony门平台在复杂的结构性心脏病干预中具有适应性.
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