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缺少STING促进了小鼠在腕根突破后的运动恢复

Yu Peng1,2, Ying Zhang3, Shenhui Yang4

  • 1Department of Neurology, Multi-Omics Research Center for Brain Disorders, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.

Animal models and experimental medicine
|December 10, 2025
PubMed
概括

抑制STING信号可以通过减少运动神经元死亡和神经炎症,改善臂根突变 (BPRA) 后的运动恢复. 这表明STING抑制是BPRA的潜在治疗方法.

关键词:
支臂根突破 (BPRA) 是一种手臂根突破.运动神经元 (MN)神经炎症是一种神经炎症.干扰素基因 (STING) 的合成刺激剂.

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