关于使用大麻治疗子宫内膜异位症的综合系统性审查
Kindha McLaren1, Simon Erridge1,2, Mikael H Sodergren1,2
1Medical Cannabis Research Group, Imperial College London, London, UK.
The Australian & New Zealand journal of obstetrics & gynaecology
|December 10, 2025
概括
大麻在减少子宫内膜异位症疼痛方面表现有前途,大多数使用者报告改善. 然而,需要进行更严格的研究来确认其在子宫内膜异位症治疗中的安全性和有效性.
科学领域:
- 医学研究 医学研究
- 药理学 药理学是指药理学的学科.
- 妇女健康 妇女健康
背景情况:
- 子宫内膜异位症影响6-10%的女性,导致严重的疼痛和不孕.
- 目前对子宫内膜异位症的治疗有局限性.
- 人们越来越感兴趣使用大麻来治疗子宫内膜异位症的症状.
研究的目的:
- 审查大麻对子宫内膜异位症相关疼痛的影响.
- 在子宫内膜异位症患者中记录与大麻使用相关的不良事件.
主要方法:
- 在PubMed,MEDLINE和EMBASE上进行了全面的文献搜索.
- 包括的研究是人类或临床试验评估大麻在非怀孕的成年人与子宫内膜异位症.
- 搜索是在2024年1月16日进行的.
主要成果:
- 包括13项研究 (9项已完成,4项正在进行),已完成的研究有1787名参与者.
- 缓解疼痛是大麻使用的主要原因 (57.3%-95.5%).
- 大多数研究报告了感知疼痛的改善,常见的不良事件包括高兴感和口腔干燥.
结论:
- 观察性研究表明,大麻可以缓解子宫内膜异位症的疼痛.
- 缺乏高质量的前性和随机对照试验.
- 进一步的随机对照试验对于评估医用大麻对子宫内膜异位症的疗效和安全至关重要.
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