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Updated: Jan 9, 2026

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用于生物医学研究的基于MS的甘氨基化合物的进展

Joy Solomon1, Akeem Sanni1, Waziha Purba1

  • 1Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, TX 79409-1061, USA. joy.solomon@ttu.edu.

Analytical methods : advancing methods and applications
|December 10, 2025
PubMed
概括

使用质谱法 (MS) 进行的糖化分析正在快速推进. 新的MS技术和计算工具改善了甘氨酸结构预测和数据解释,用于发现疾病生物标志物.

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Protein Glycosylation01:25

Protein Glycosylation

Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
Glycosylation occurs in...
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