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Updated: Jan 9, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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遗传多态性是否会影响慢性髓性白血病患者的伊马替尼的最低度? 一个系统的审查和元分析

Francisco Cezar Aquino de Moraes1, Gustavo Tadeu Freitas Uchôa Matheus2, Luis Henrique Rios Moreira Rego3

  • 1Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil.

Expert review of anticancer therapy
|December 10, 2025
PubMed
概括

在ABCB1和ABCG2的遗传变异显著影响慢性髓性白血病 (CML) 的伊马替尼治疗. 药物遗传查可以通过识别可能发生意马替尼度变化的患者来优化治疗疗效和安全性.

关键词:
在ABCB1中,ABCB1是ABCB1.这就是ABCG2ABCG2.慢性骨髓性白血病 慢性骨髓性白血病伊马替尼布 (Imatinib) 的使用情况这是一个元分析.

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