肠道微生物群衍生代谢物在调节家禽免疫代谢中的作用
O E Oke1, L O Fasasi1, I O Opowoye2
1Department of Animal Physiology, Federal University of Agriculture, Abeokuta, Nigeria.
Frontiers in physiology
|December 10, 2025
概括
禽类的肠道微生物产生代谢物,调节鸟类的免疫和新陈代谢. 了解这些相互作用对于可持续的家禽生产,改善健康和减少抗生素需求至关重要.
科学领域:
- 动物科学动物科学
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
背景情况:
- 禽畜生产面临着热应激,疾病和抗生素限制等挑战.
- 免疫代谢,连接免疫和代谢,对于家禽的健康和生产力至关重要.
- 肠道微生物群充当代谢器官,产生影响宿主健康的生物活性代谢物.
研究的目的:
- 审查家禽肠道微生物群的组成和功能.
- 解释鸟类免疫代谢和微生物代谢物调节.
- 评估旨在优化代谢物概况和家禽结果的干预措施.
主要方法:
- 关于禽类肠道微生物群,免疫代谢和微生物代谢物的文献综述.
- 对将微生物代谢物与宿主免疫代谢调节联系起来的机制的分析.
- 强调新兴技术,如代谢学,元基因组学和系统生物学.
主要成果:
- 微生物群衍生代谢物显著影响家禽的免疫代谢,影响疾病抵抗力,应激适应能力和疫苗接种反应.
- 这些代谢物调节肠道屏障完整性,能量平衡,氧化应激和免疫细胞激活.
- 营养和管理干预可以塑造有益的代谢物概况.
结论:
- 肠道微生物群的代谢物对家禽的免疫代谢至关重要,为精准营养和医疗保健提供了途径.
- 需要使用综合方法进行进一步的研究,以加强可持续和有弹性的家禽生产.
- 准代谢物-免疫轴为改善家禽健康和生产率提供了机会.
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