在多重 evanescent 白点综合征中对立的病理理学概念:伟大的MEWDS分裂
Carl P Herbort1, Ioannis Papasavvas1,2, Abdulrahman F Albloushi3
1Retinal and Inflammatory Eye Diseases, Centre for Ophthalmic Specialised Care, Lausanne, Switzerland.
概括
多重 evanescent 白点综合征 (MEWDS) 涉及外视网膜和胆. 有证据表明,MEWDS源于末端胆囊膜不 perfusion,导致二次光受体损伤,自发分辨率.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 排卵管炎 排卵管炎 是一种
背景情况:
- 多发 evanescent白点综合征 (MEWDS) 是一种良性后膜炎,会影响外视网膜和胆.
- 经典分类认为MEWDS是一种毛囊炎,但其他理论建议光受体炎作为主要病变.
- 了解病理生理学对于准确的诊断和管理至关重要.
研究的目的:
- 审查现有的文献,并提供证据,以提供MEWDS的可靠的病理生理学解释.
- 突出印氨酸绿色血管学 (ICGA) 在了解MEWDS中的作用.
- 挑战ICGA低光度的RPE非吸收论文.
主要方法:
- 文献综述和整合关于MEWDS的原始研究研究.
- 分析氨酸绿色血管学 (ICGA) 发现.
- 在MEWDS中对光学连贯性断层扫描血管学 (OCTA) 局限性的评估.
主要成果:
- 在MEWDS中ICGA的低光度表明输液问题,而不是RPE不吸收,在血管学早期出现.
- 缺氧损伤主要影响光受体,对视网膜色素上皮质 (RPE) 细胞的影响最小.
- 由于无法检测低流量末端毛细血管的流量,OCTA被认为不适合MEWDS.
结论:
- MEWDS源于末端胆囊细胞不 perfusion,导致光受体的二次缺氧损伤.
- 在MEWDS和其他胆囊炎实体之间存在连续性,所有实体都涉及炎症性胆囊性循环功能障碍.
- 由于小末端胆毛囊血管的参与,没有后续的自发解脱是典型的.
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