动脉活检:对当前实践的10年多中心审查
Adrian J Tam1, Samantha Leng1, Christopher Steen2
1General Surgery, Eastern Health, Ringwood, AUS.
Cureus
|December 10, 2025
概括
动脉活检 (TAB) 在指导巨细胞动脉炎 (GCA) 治疗方面具有有限的实用性. 许多患者不管活检结果如何,都继续接受类固醇治疗,这表明需要改进诊断标准.
科学领域:
- 类风湿病学 类风湿病学
- 血管外科 血管外科
- 组织病理学 组织病理学
背景情况:
- 巨细胞动脉炎 (GCA) 的诊断通常依赖于动脉活检 (TAB).
- 在管理GCA中TAB的临床实用性需要进一步研究.
研究的目的:
- 评估TAB在诊断GCA时的临床实用性.
- 评估TAB对随后的GCA医疗管理的影响.
主要方法:
- 对接受TAB的216名患者进行了10年的回顾性分析.
- 收集的数据包括患者的风险因素,手术前的类固醇使用,活检样本长度和组织病理学发现.
主要成果:
- 80.6%的患者在TAB之前开始服用类固醇.
- 只有18.5%的TABs在他的病理学上是阳性的.
- 37.3%的阴性TAB患者完成了类固醇治疗,14.9%接受了TAB,尽管事先有记录的计划,无论结果如何,都会继续使用类固醇.
结论:
- 在指导GCA医疗管理方面,TAB的实用性有限.
- 有相当数量的患者继续接受类固醇治疗,无论活检结果如何.
- 需要改善临床概率得分,以指导类固醇戒断.
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