缩性肺骨关节病作为肺癌的初始表现
Sarra K Mohamed Ahmed1, Yara K Mohamedahmed2, Lana Fadl3
1Internal Medicine, Walsall Manor Hospital, Walsall, GBR.
Cureus
|December 10, 2025
概括
缩性肺性骨关节炎 (HPOA),一种神经发育综合征,可以模仿类风湿性关节炎. 即使没有呼吸道症状,对于无法解释的关节疼痛和数字俱乐部患者来说,早期诊断至关重要.
科学领域:
- 医学案例报告 病例报告
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
背景情况:
- 缩性肺性骨关节病 (HPOA) 是一种神经瘤综合征.
- 它通常表现为数字俱乐部,周节炎和关节痛,通常与肺癌有关.
- 这种综合征可以模仿其他类风湿病.
研究的目的:
- 报告肺部恶性瘤的二次性HPOA病例.
- 突出诊断挑战和考虑瘤综合征的重要性.
- 强调需要在患者中高度临床怀疑不明原因的关节病和数字俱乐部.
主要方法:
- 一个60多岁的男性患者的病例报告.
- 最初的调查包括类风湿因子 (RF) 和抗素 (anti-CCP) 抗体测试.
- 诊断成像包括胸部X射线和CT扫描,随后进行活检以确定诊断.
主要成果:
- 患者出现了渐进的关节疼痛,四肢胀和数字扩大.
- 最初的检查表明类风湿性关节炎,但后来确认了肺癌.
- 通过活检诊断出左下叶状细胞癌.
结论:
- HPOA可能是肺癌的早期表现.
- 在无法解释的关节病和数字俱乐部的情况下,保持高HPOA怀疑指数至关重要.
- 诊断延迟可能会发生,如果瘤综合征没有及时考虑,即使没有明显的呼吸道症状.
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