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在癌症患者中,营养干预是否有价值? 关于经济评估的系统审查
Hieu Thi Thanh Nguyen1, Arthorn Riewpaiboon2, Hien Thi Bich Tran3
1Social, Economic and Administrative Pharmacy (SEAP) Graduate Program, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, Thailand.
ClinicoEconomics and outcomes research : CEOR
|December 10, 2025
概括
营养干预可以改善癌症患者的结果和生活质量. 一些研究表明,组合营养策略具有成本效益,为治疗优化和政策决策提供指导.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 营养科学 营养科学
背景情况:
- 营养不良是癌症患者的一个重要问题,受瘤进展和治疗的影响.
- 营养干预措施有望提高治疗效率和患者的生活质量.
- 这些干预措施的成本效益需要进行系统的经济评估.
研究的目的:
- 系统地审查癌症患者营养干预措施的经济评估.
- 评估预防和治疗营养策略的成本效益.
- 为临床和政策决策提供证据.
主要方法:
- 在PubMed和Scopus数据库中的系统文献搜索.
- 评估报告质量,使用综合健康经济评估报告标准 (CHEERS) 清单进行评估.
- 使用证据和成本偏差评估 (ECOBIAS) 检查清单评估偏差风险.
主要成果:
- 八项研究 (1989-2022) 专注于高收入国家的胃肠道癌症.
- 六项研究使用了成本效益分析;四项研究表明,口服/肠道营养与咨询的联合营养的成本效益.
- 大多数研究符合CHEERS标准,但缺乏异质性分析和利益相关者参与讨论. 常见的偏见包括灵敏度分析,生活质量权重和范围限制.
结论:
- 营养干预措施,特别是联合策略,在癌症治疗中显示出潜在的成本效益.
- 这些发现可以指导医生优化患者治疗.
- 结果可以为有关癌症患者营养支持的卫生政策决策提供信息.
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