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Updated: Jan 9, 2026

Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated Protein
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Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated Protein

Published on: January 16, 2020

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替代拼接KRAS外形4通过增强KRAS4A瘤活性促进瘤进展

Namjoon Cho1, Eunhye Kwon1, Si-Eon Kim1

  • 1Department of Biochemistry, College of Natural Sciences, Chungnam National University, Daejeon, Republic of Korea.

Animal cells and systems
|December 10, 2025
PubMed
概括

这项研究表明,KRAS4A是一种KRAS拼接变体,增强了癌症的致癌性质. 关键调节器RBM47和PTBP1促进KRAS替代拼接,为癌症治疗提供新的治疗点.

关键词:
克拉斯 (Kras) 是一个国家.替代性拼接是一种替代性的拼接.癌症进展 癌症进展在基因上,我们发现了基因上的差异.拼接因素 拼接因素

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