选择性激光形术在泰国玻璃眼患者初始,辅助和替代疗法的临床结果
Kulawan Rojananuangnit1, Fahsiri Tavonvunchai1, Rinrada Kreesang1
1Department of Ophthalmology, Mettapracharak (Wat Rai Khing) Hospital, Nakhon Pathom, Thailand.
Clinical ophthalmology (Auckland, N.Z.)
|December 10, 2025
概括
选择性激光轨道造形术 (SLT) 在泰国绿眼患者中显示出有效性,特别是在初始或替代疗法中. 较高的基线眼内压力和药物使用预测较差的结果,突出需要个性化治疗策略.
科学领域:
- 眼科医生 眼科 眼科
- 视光眼管理 视光眼管理
- 激光疗法是一种激光疗法.
背景情况:
- 选择性激光轨道造形术 (SLT) 是一种常见的玻璃眼治疗方法.
- 在不同患者群体和治疗环境中评估SLT结果对于优化临床实践至关重要.
研究的目的:
- 评估选择性激光形造形术 (SLT) 在泰国绿眼患者的有效性和耐用性.
- 在初始,辅助和替代疗法组中比较SLT结果.
- 确定治疗反应和长期疗效的预测因素.
主要方法:
- 从123名泰国绿眼病患者的254只眼睛进行了回顾性分析,这些患者接受了SLT.
- 分类为初始,辅助和替代疗法组.
- 卡普兰-梅尔治疗耐久性的生存分析和用于预测因子识别的多变量回归模型.
主要成果:
- 总体激光响应率为61.1%,在各组之间存在显著差异 (初始:78.9%,替代:68.9%,辅助:45.3%).
- 终身教育的平均有效持续时间为1.5年;累计成功率为67.2%在1年和14.7%在3年.
- 较高的基线眼内压,增加的药物使用和阿扎胺与不响应有关. 老年,较高的基线内血压和更多的药物预测了治疗效果的缩短.
结论:
- 选择性激光轨道造形术 (SLT) 在泰国绿眼患者中是有效和可重复的,特别是作为初始或替代疗法.
- 辅助SLT提供了一些好处,但较高的基线眼内压和药物负担可能会导致疗效降低.
- 个性化的患者选择和及时的再治疗是最大化SLT结果的关键.
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