动脉食管: 长期生存与积极的多学科管理
Rolando Calderon-Rojas1,2, Brett Curran1,2, Belisario A Ortiz1
1Division of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
JTCVS techniques
|December 10, 2025
概括
动脉食管 (AoEF) 是一种罕见的,高死亡率的疾病. 积极的,涉及食道和大动脉修复的多学科治疗为选定的患者提供了良好的长期生存率.
科学领域:
- 心血管外科心血管外科
- 胃肠道手术 胃肠道手术
- 胸部外科手术 胸部外科手术
背景情况:
- 动脉食管 (AoEF) 是一种罕见且危及生命的疾病.
- 高死亡率与AoEF有关,需要有效的管理策略.
研究的目的:
- 描述机构在治疗大脑食道 (AoEF) 方面的经验.
- 分析AoEF各种治疗方式的结果.
主要方法:
- 在2005年至2023年期间对17名AoEF患者进行了回顾性审查.
- 分析基线特征,诊断评估,手术治疗和后续数据.
- 使用卡普兰-梅尔方法和日志等级测试评估的整体存活率 (OS).
主要成果:
- 大多数患者先前接受过大动脉手术 (71%). 病因包括大动脉疾病 (76%) 和食道切除术后的解性泄漏 (24%).
- 十二名患者 (67%) 接受了治疗意图的治疗,包括转移食道切除术和大动脉置换,使用里法浸泡的移植或同位移植.
- 在接受治疗的患者中,住院死亡率为8%;1年和2年OS率分别为83%和74%,在没有治疗意图的病例中存活率明显较低.
结论:
- 管理AoEF是复杂的,需要一个多学科的方法.
- 绝对的食道和大动脉修复,当积极地进行时,可以在选择的AoEF患者中导致有利的长期存活.
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