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社区药房发行错误:对趋势和解决方案的全面系统审查
Azadeh Eshraghi1, Niloofar Madani1, Hamidreza Aslani1
1Department of Clinical Pharmacy and Pharmacoeconomics, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran.
Journal of research in pharmacy practice
|December 10, 2025
概括
药房发行错误很常见,特别是在社区环境中,错误的剂量和类似的药物名称是经常出现的问题. 结合技术和人员培训的多模式策略可以减少这些重大患者安全风险.
科学领域:
- 药房实践 在药房实践.
- 患者安全 患者安全
- 改善医疗保健质量 改善医疗保健质量
背景情况:
- 药店的错误分发带来了严重的患者安全风险,并在全球范围内增加了医疗保健成本.
- 关于药物发行错误的流行率,原因和有效干预措施的综合性研究有限.
研究的目的:
- 系统地审查当前有关门诊和社区药房的发行错误流行情况的证据.
- 确定导致发行错误的关键风险因素.
- 评估缓解策略对减少发药错误的影响.
主要方法:
- 在PubMed,Embase和CINAHL (2010年1月至2025年6月) 中按照PRISMA指南进行系统的文献搜索.
- 包括22项研究 (13个发展中国家,9个发达国家) 报告可计算的患病率.
- 数据提取和偏差评估使用NHLBI和GRADE工具,由两个独立审查员进行.
主要成果:
- 分发错误率差异很大 (0.001%-11.53%),在社区 (平均4.12%) 比门诊药房 (1.85%) 高.
- 常见的错误包括错误的剂量/强度 (58.6%) 和外观/声音相似的药物混 (47.90%).
- 主要因素是工作量高 (55%),人员短缺 (22%) 和无法阅读的处方 (30.70%).
结论:
- 发行错误仍然是一个关键问题,特别是在社区药房和服务不足的地区.
- 综合技术,标准化工作流程和员工培训的多模式策略显示出减少错误的潜力.
- 证据的确定性非常低,需要使用一致的方法和强大的错误报告系统进行进一步的研究.
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