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Updated: Aug 1, 2026

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检测新的HLA-B*35:01:86和HLA-DRB1*15:243等位基因

Maria Loginova1,2, Igor Paramonov1, Maksim Zarubin3

  • 1Federal State-Financed Scientific Institution: Kirov Research Institute of Hematology and Blood Transfusion Under the Federal Medical Biological Agency, Kirov, Russia.

HLA
|December 10, 2025
PubMed
概括

发现了新的人类白细胞抗原 (HLA) 基因,特别是HLA-B*35:01:86和HLA-DRB1*15:243. 这些发现有助于对HLA遗传多样性的日益增长的理解.

关键词:
HLA-B HLA-B 是一个很好的方法.在HLA-DRB1中.国家储备系统 (NGS)一个新型的等位基因

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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