沙风驱动的颗粒物暴露和中国干旱地区COPD住院风险增加:时空流行病学分析
Hao Zhao1, Ce Liu1, Er Kai Zhou1
1Institute of Occupational Health and Environmental Health, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Biomedical and environmental sciences : BES
|December 10, 2025
概括
在沙尘暴期间暴露于颗粒物,显著增加了中国西北部慢性阻塞性肺病 (COPD) 的住院风险. 这种风险在男性,老年人和寒冷的月份更高,强调需要有针对性的公共卫生战略.
科学领域:
- 环境健康 环境健康
- 呼吸系统医学 呼吸系统医学
- 流行病学 流行病学
背景情况:
- 慢性阻塞性肺病 (COPD) 在中国西北地区造成了严重的健康负担.
- 沙尘暴对干旱地区COPD住院治疗的具体影响尚不清楚.
研究的目的:
- 调查中国干旱地区在SDS日期间的PM暴露与COPD住院风险之间的关联.
主要方法:
- 一个时空分层的病例交叉设计被用来分析来自甘省323家医院的265,379例COPD住院病例 (2018-2022).
- 每天收集空气污染物 (PM2.5) 和气象数据.
- 使用有条件的波桑回归模型来评估风险.
主要成果:
- 在SDS日的PM暴露与COPD住院风险增加显著相关 (PM2.5的RR,滞后3: 1.028,95%CI: 1.021-1.034).
- 风险在男性,老年人和寒冷季节显著增加.
- 在中国西北的干旱和半干旱地区,观察到对COPD住院病人的PM暴露的实质性负担.
结论:
- 在SDS发作期间的PM暴露与中国干旱和半干旱地区的COPD住院病例正相关.
- 迫切需要特定区域的公共卫生战略,以减轻与SDS相关的空气质量恶化相关的呼吸系统不良结果.
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