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Updated: Jan 9, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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开发和验证四种胆酸作为CYP3A药物相互作用生物标志物的同时分析方法

Zhiyin Xun1, Lin Zhang1, Ryan McGee1

  • 1Drug Metabolism and Non-Clinical Pharmacokinetics, Incyte Research Institute, Wilmington, DE, USA.

Bioanalysis
|December 10, 2025
PubMed
概括

一种新的LC-MS/MS方法量化了人体血中的四种脱氧胆酸生物标志物,用于评估药物相互作用. 这种经过验证的试验为评估由CYP3A介导的药物相互作用提供了一个强大的平台.

关键词:
1β-氧二氧化胆酸是1β-氧化胆酸.胆酸是什么意思 胆酸是什么意思在CYP3A.在 LCMS/MS 中使用.生物分析是一种生物分析.生物标志物生物标志物脱氧胆酸脱氧胆酸是什么药物 药物相互作用

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